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137, 807 (2006) , (8) J.B

The o-quinones can covalently bind to nucleophiles such as cysteine, lysine, or histidine residues of proteins [169]

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This Fc domain serves a dual function: it sterically hinders access to DPP-4, thereby protecting the GLP-1 moiety from enzymatic degradation, and it engages the neonatal Fc receptor (FcRn), facilitating receptor-mediated recycling and preventing lysosomal degradation following cellular uptake